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Accutane Psychiatric Disorders

WARNINGS: Psychiatric disorders: Accutane may cause depression, psychosis and, rarely, suicidal ideation, suicide attempts, suicide, and aggressive and/or violent behaviors. Discontinuation of Accutane therapy may be insufficient; further evaluation may be necessary.

ADVERSE SIDE EFFECTS: Psychiatric: Suicidal ideation, suicide attempts, suicide, depression, psychosis, aggression, violent behaviors, emotional instability. /psychiatric-disorders

Since 1982 the FDA has reported 173 cases of suicide amongst users of Accutane. Though this number may be surprisingly high, in actuality it is most likely a low estimate. The FDA estimates that only 1% of the adverse suicides are reported. Thus putting the number of Accutane related suicides as high as possibly 20,000.

As early as February 1985 Suicide and depression came to the attention of the FDA as possible side effects of the drug. There was a case of suicide reported where the patient had no history of depression. Physicians have been told that simply terminating Accutane treatment might not adequately treat psychiatric disorders and that patients may require additional psychiatric therapy.

It has been reported that some patients, during treatment with Accutane or soon after completing treatment, have experienced depression or other serious mental problems. Symptoms of these problems include:

Irritability

Anger

Loss of pleasure of interest in life

Sleeping too much or too little

Changes in weight or appetite

Trouble concentrating

Suicide

Suicidal thoughts

Suicidal attempts

Depression

Aggression

Paranoia

Violent behaviors

Psychosis

Personality changes

Mood swings

Withdrawal

Abnormal behaviors

Notify your physician if you or someone in your family has ever had any mental illness, including depression, suicidal behavior or psychosis. Also, notify your physician if you take medications for any of these problems.

Notify your physician immediately if you experience any of the following symptoms:

Feelings of sadness or crying spells

Loss of interest in activities

Sleeping too much or insomnia

Irritability

Change in appetite or body weight

Trouble concentrating

Withdrawing from friends and family

Loss of energy

Feelings of worthlessness or unfounded guilt

Suicidal thoughts

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Have you or loved one used Accutane® or Generic Isotretinoin?

Have you or loved one been MEDICALLY DIAGNOSED BY A DOCTOR with any of the following conditions within 5 years of using Accutane®?

Symptoms of IBD/IBS with no medical diagnosis

Irritable Bowel Syndrome (IBS)

Inflammatory Bowel Disease (IBD)

Ulcerative Colitis

Crohn's Disease

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Accutane Psychiatric Disorders

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